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An Andropause Clinic

What is Andropause?

Andropause refers to the age-related decline in testosterone production in men. Starting around age 30, testosterone levels drop gradually, typically about 1% per year, without a defined start or end point.

Because the decline is slow, most men adapt to it without realizing anything has changed. Symptoms build quietly over years, and by the time they're noticeable, they're often attributed to stress, poor sleep, or simply getting older.

Man, midlife, evaluating symptoms of andropause at Xena Health
By The Numbers
~30
Age testosterone typically begins its gradual decline
~1%
Approximate annual decline in total testosterone thereafter
40+
Age range where symptoms are most commonly identified and evaluated
Andropause isn't diagnosed by age or symptoms alone.

A proper evaluation requires lab-confirmed low testosterone plus a symptom picture that fits, not a single number or a feeling. See how Xena Health evaluates low testosterone.

Symptoms of Andropause

Gradual, wide-ranging & easy to dismiss

Because the decline happens slowly, andropause symptoms are frequently attributed to stress, aging, or overwork rather than hormones. A comprehensive lab panel is the only way to know what's actually driving them.

Physical & Energy
What you'll feel first
Persistent fatigue
Reduced exercise recovery
Reduced muscle mass or strength
Increased body fat
Reduced bone density
Mood & Cognition
The ones most often misread
Difficulty concentrating, brain fog
Lower motivation or drive
Irritability or mood changes
Flat affect or low mood
Sexual Health
Changes that affect intimacy
Low libido
Erectile or sexual-function changes
Reduced morning erections
Sleep
Why rest doesn't fix it
Difficulty falling or staying asleep
Waking unrefreshed
Daytime sleepiness
Metabolic
Body composition changes
Weight gain despite no diet change
Abdominal weight redistribution
Slower metabolism
Cardiovascular
Less commonly recognized
Reduced exercise tolerance
Hot flashes or sweating changes
Hair thinning
Before You Assume It's Low-T

What can mimic the symptoms of low testosterone?

Fatigue, low libido, weight gain, and mood changes aren't unique to andropause. Several common conditions overlap heavily with low-T symptoms, which is why lab confirmation matters more than a symptom checklist.

Frequently Overlooked
Obstructive Sleep Apnea (OSA)

OSA causes fatigue, low libido, brain fog, and irritability, the same core complaints as low testosterone, and the two conditions frequently occur together. Untreated OSA can also independently suppress testosterone production, and starting TRT without addressing underlying sleep apnea may not resolve symptoms and can worsen OSA in some men. If snoring, witnessed pauses in breathing, or unrefreshing sleep are part of your history, that's worth flagging at your evaluation.

Thyroid Dysfunction
An underactive thyroid produces fatigue, weight gain, low mood, and reduced libido that closely overlap with low-T. Thyroid labs are part of a proper workup.
Depression & Chronic Stress
Low mood, low motivation, and fatigue can stem from mental health or chronic cortisol elevation as easily as from hormones, and the two often coexist.
Metabolic Conditions
Type 2 diabetes and obesity are both linked to lower testosterone and can independently cause fatigue, weight gain, and reduced exercise tolerance.
Book a Lab Consultation
If Labs Confirm Low Testosterone

Treatment starts with the right diagnosis.

If a comprehensive hormone panel confirms low testosterone, Xena Health offers individualized TRT: injections, EvexiPEL pellets, or topical creams, with ongoing monitoring for men in Las Vegas and Henderson, plus telehealth across Nevada, Arizona, and Utah.